Ipilimumab Approaches EU Approval for Pediatric Melanoma

The European Medicines Agency’s Committee for Medicinal Products for Human Use (CHMP) has recommended approval of ipilimumab (Yervoy) for the treatment of pediatric patients aged 12 years and older with unresectable or metastatic melanoma, according to Bristol-Myers Squibb (BMS), the manufacturer of the CTLA-4 inhibitor.

First-in-class ERK1/2 Inhibitor Safe, Shows Early Efficacy In Patients With Advanced Solid Tumors

The novel ERK1/2 kinase inhibitor ulixertinib displayed an acceptable safety profile and had clinical activity in patients whose tumors had mutations in the MAPK cell-signaling pathway, according to data from a phase I clinical trial published in Cancer Discovery, a journal of the American Association for Cancer Research.

New Cancer Drug Shows Promise Against Many Tumors

A new drug that targets a genetic flaw common to most cancer cells is showing potency against many tumor types.

Real-Time Monitoring of Melanoma Cell Invasion Helps Scientists Elucidate Key Regulators of Metastasis

SAN DIEGO–(BUSINESS WIRE)–A team of Italian scientists reported this week that blocking the interaction between urokinase receptor (uPAR) and formyl peptide receptor type 1 (FPR1) suppresses the ability of melanoma cells to migrate, invade through an extracellular matrix, and to burrow through a layer of endothelial cells.

Cancer in the News

Feature Articles

Yackandandah Man Spreads Awareness Of Melanomas Not Caused By UV Rays

A melanoma unrelated to sun exposure began as a black smudge on the ball of Tim Roberts’ right foot.

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Posted in Melanoma In The News, Patient Stories

Arthritis Drug Could Help Treat Advanced Skin Cancer

Treatment for the most deadly form of skin cancer could be more effective if combined with a well-known drug for rheumatoid arthritis, new research has shown.

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Posted in Melanoma In The News, Information

Arthritis Drug Could Help Treat Advanced Skin Cancer

Treatment for the most deadly form of skin cancer could be more effective if combined with a well-known drug for rheumatoid arthritis, new research has shown.

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Posted in Melanoma In The News, Information

EMA’s CHMP Recommends Yervoy for Patients 12 and Older with Advanced Melanoma

Yervoy (ipilimumab) has received a positive review by the European Medicines Agency (EMA)’s Committee for Medicinal Products for Human Use (CHMP), recommending its approval for the treatment of unresectable or metastatic melanoma in patients age 12 and older.

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Posted in Melanoma In The News, European Approval

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Melanoma Google Alerts is a summary of daily articles found in print and on the internet. The articles do not necessarily represent the views of Melbourne Melanoma Project

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