Archive | Clinical Trials

COMBI-v BRAF/MEK Inhibitor Combination Trial Continues to Impress in Melanoma

For advanced melanoma patients with BRAF mutations, two pathway inhibitors are much better than one, according to a study presented at the European Society for Medical Oncology.

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Posted in Melanoma In The News, Clinical Trials

Binimetinib Delayed Progression of NRAS-Mutant Melanoma

The MEK inhibitor binimetinib improved progression-free survival compared with dacarbazine in patients with NRAS-mutant melanoma, according to the phase III results of the NEMO trial published in Lancet Oncology.

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Posted in Melanoma In The News, Clinical Trials

Array BioPharma Provides NEMO Update

BOULDER, Colo., March 19, 2017 /PRNewswire/ — Array BioPharma Inc. (Nasdaq: ARRY) today announced that it has withdrawn from the U.S. Food and Drug Administration’s (FDA) Division of Oncology Products 2 its new drug application (NDA) for binimetinib monotherapy for the treatment of NRAS-mutant melanoma, a rare, mutationally-driven subset of skin cancer.

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Posted in Melanoma In The News, Clinical Trials

Intratumoral therapy increases response to checkpoint inhibitor for melanoma

The phase 2 registration trial designed to evaluate ImmunoPulse IL-12 in combination with pembrolizumab for unresectable metastatic melanoma showed an increase in response rates among patients who were not expected to respond to anti–PD-1 therapy alone.

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Posted in Melanoma In The News, Clinical Trials

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Melanoma Google Alerts is a summary of daily articles found in print and on the internet. The articles do not necessarily represent the views of Melbourne Melanoma Project

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