Dartmouth Researchers Find Tumor-Killing T-Cells In The Skin To Fight Melanoma

Source: University Herald, April 2017

Researchers at Dartmouth College’s Norris Cotton Cancer Center published a study about how they discovered unique immune cells. These are deemed as resident memory T cells and are the ones that battle melanoma.

They observed that patients with melanoma, who develop vitiligio, have a good prognosis. Vitiligo is an autoimmune skin condition that works against normal healthy melanocytes and causes the loss of skin pigmentation in blotches.

MedicalXpress reported that the team studied mouse models of melanoma and vitiligo and found that resident memory T cells permanently reside in vitiligo-affected skin. These kill melanoma cells.

Resident memory T cells were already known to prevent skin viral infection. However, it was not known until now that they could fight tumors.

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