Indoximod plus pembrolizumab prompts response in advanced melanoma

The addition of investigational immunotherapy indoximod to pembrolizumab conferred superior response rates in patients with advanced melanoma, according to interim results of a phase 2 clinical trial presented at the American Association for Cancer Research Annual Meeting.

VIDEO: Molecular alterations may identify intermediate stages of melanoma progression

NEW YORK — Boris C. Bastian, MD, PhD, director of the Clinical Cancer Genomics Laboratory at Hellen Diller Family Comprehensive Cancer Center of University of California, San Francisco, discusses UV–associated molecular alterations that affect melanoma progression at HemOnc Today Melanoma and Cutaneous Malignancies.

First Phase 3 OS Results With Melanoma ImmunoTx Combo

Nivolumab (Opdivo, Bristol-Myers Squibb) — alone or in combination with ipilimumab (Yervoy, Bristol-Myers Squibb) — improved overall survival (OS) in treatment-naive patients with advanced melanoma compared with ipilimumab alone, according to new findings.

New study reveals how some chickens got striped feathers

Birds show an amazing diversity in plumage colour and patterning. But what are the genetic mechanisms creating such patterns?

Cancer in the News

Feature Articles

Understanding response and resistance to cancer therapy: Lessons learned from melanoma

Dr Wargo speaks with ecancer at AACR 2017 about understanding the mechanisms of resistance in treating tumours, considering the influence of epigenetics, the tumour microenvironment and microbiota among others.

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Posted in Melanoma In The News, Other Melanoma Research

Matching tumour size to strength of immune response allows melanoma drug tailoring

Despite the success of immunotherapies based on blocking the programmed cell death 1 (PD-1) receptor protein in metastatic melanoma patients, more than half do not experience a lasting benefit by seeing their tumours shrink.

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Posted in Melanoma In The News, Other Melanoma Research

Dermoscopic Evaluation of Seborrheic Keratosis Can Help Diagnose Melanoma

A new study has identified several characteristics that can help to detect seborrheic keratosis (SK)–like melanomas using dermoscopy, including the presence of the blue-black sign, pigment network, pseudopods or streaks, and/or a blue-white veil.

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Posted in Melanoma In The News, Information

Assessment of Melanoma Screening Practices Produces Data-Driven, Risk-Based Guidelines

More than 50 dermatologists assessed screening practices for melanoma in a perspective study published recently in Melanoma Management that aimed to address the fact that currently no national consensus exists on skin cancer screening in the United States.

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Posted in Melanoma In The News, Information

Melanoma Google Alerts

Melanoma Google Alerts is a summary of daily articles found in print and on the internet. The articles do not necessarily represent the views of Melbourne Melanoma Project

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