Understanding response and resistance to cancer therapy: Lessons learned from melanoma

Source: eCancer News, April 2017

Dr Jennifer Wargo – The University of Texas MD Anderson Cancer Center, Houston, USA

Dr Wargo speaks with ecancer at AACR 2017 about understanding the mechanisms of resistance in treating tumours, considering the influence of epigenetics, the tumour microenvironment and microbiota among others.

The influence of the microbiome on cancer risk and treatment response was reviewed in an ecancer article last year, and she describes how research in mouse models translates to human trials.

Dr Wargo previously discussed the influence of the gut microflora on immunotherapy response at NCRI 2016.

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